Synthesis and conformational analysis of cyclic analogues of inverse gamma-turns.
Gamma-turn analogues comprising a modified dipeptide constrained in an eleven-membered ring were prepared by alkene metathesis and analysed by NMR and molecular modelling studies. The results reveal that some of the cyclic analogues form inverse gamma-turns and preferentially adopt conformations det...
| Main Authors: | , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2008
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| _version_ | 1797062455838375936 |
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| author | Kaewpet, M Odell, B King, M Banerji, B Schofield, C Claridge, T |
| author_facet | Kaewpet, M Odell, B King, M Banerji, B Schofield, C Claridge, T |
| author_sort | Kaewpet, M |
| collection | OXFORD |
| description | Gamma-turn analogues comprising a modified dipeptide constrained in an eleven-membered ring were prepared by alkene metathesis and analysed by NMR and molecular modelling studies. The results reveal that some of the cyclic analogues form inverse gamma-turns and preferentially adopt conformations determined by the identity of the incorporated amino acid residues and the nature of the constraining linker (E/Z-alkene or alkane). |
| first_indexed | 2024-03-06T20:45:48Z |
| format | Journal article |
| id | oxford-uuid:35d7bf3a-9d28-4477-aff2-4cc1e280c64b |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T20:45:48Z |
| publishDate | 2008 |
| record_format | dspace |
| spelling | oxford-uuid:35d7bf3a-9d28-4477-aff2-4cc1e280c64b2022-03-26T13:34:21ZSynthesis and conformational analysis of cyclic analogues of inverse gamma-turns.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:35d7bf3a-9d28-4477-aff2-4cc1e280c64bEnglishSymplectic Elements at Oxford2008Kaewpet, MOdell, BKing, MBanerji, BSchofield, CClaridge, TGamma-turn analogues comprising a modified dipeptide constrained in an eleven-membered ring were prepared by alkene metathesis and analysed by NMR and molecular modelling studies. The results reveal that some of the cyclic analogues form inverse gamma-turns and preferentially adopt conformations determined by the identity of the incorporated amino acid residues and the nature of the constraining linker (E/Z-alkene or alkane). |
| spellingShingle | Kaewpet, M Odell, B King, M Banerji, B Schofield, C Claridge, T Synthesis and conformational analysis of cyclic analogues of inverse gamma-turns. |
| title | Synthesis and conformational analysis of cyclic analogues of inverse gamma-turns. |
| title_full | Synthesis and conformational analysis of cyclic analogues of inverse gamma-turns. |
| title_fullStr | Synthesis and conformational analysis of cyclic analogues of inverse gamma-turns. |
| title_full_unstemmed | Synthesis and conformational analysis of cyclic analogues of inverse gamma-turns. |
| title_short | Synthesis and conformational analysis of cyclic analogues of inverse gamma-turns. |
| title_sort | synthesis and conformational analysis of cyclic analogues of inverse gamma turns |
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