Multidisciplinary care allowing uneventful vaginal delivery in a woman with Pompe disease
Pregnancy and delivery are challenging in women affected by Pompe disease with respiratory involvement. We describe a 28-year-old woman, who continued to receive enzyme replacement therapy during pregnancy and had an uneventful vaginal birth. Before pregnancy the patient's vital capacity was 52...
| Main Authors: | , , , , , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Elsevier
2016
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| _version_ | 1826266906480345088 |
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| author | Perniconi, B Vauthier-Brouzes, D Morélot-Panzini, C Dommergues, M Nizard, J Taouagh, N Hogrel, J-Y Canal, A Servais, L Laforêt, P |
| author_facet | Perniconi, B Vauthier-Brouzes, D Morélot-Panzini, C Dommergues, M Nizard, J Taouagh, N Hogrel, J-Y Canal, A Servais, L Laforêt, P |
| author_sort | Perniconi, B |
| collection | OXFORD |
| description | Pregnancy and delivery are challenging in women affected by Pompe disease with respiratory involvement. We describe a 28-year-old woman, who continued to receive enzyme replacement therapy during pregnancy and had an uneventful vaginal birth. Before pregnancy the patient's vital capacity was 52% in sitting position and 51% in supine position. At 32 weeks gestation her vital capacity in sitting position was 46% and 35% in supine position. Nocturnal non-invasive mechanical ventilation was introduced at this time. Labor was induced at 34 weeks following premature rupture of membranes, under epidural anesthesia. A 2590 g healthy baby was delivered by vacuum extraction. Assisted ventilation was continued throughout labor and post-partum. This observation suggests a successful pregnancy and a normal vaginal delivery can be achieved in patients with symptomatic Pompe Disease, provided multidisciplinary care is offered.
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| first_indexed | 2024-03-06T20:46:02Z |
| format | Journal article |
| id | oxford-uuid:35f14932-9d85-4a7e-8a5d-ddfa36ceea9e |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T20:46:02Z |
| publishDate | 2016 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | oxford-uuid:35f14932-9d85-4a7e-8a5d-ddfa36ceea9e2022-03-26T13:34:57ZMultidisciplinary care allowing uneventful vaginal delivery in a woman with Pompe diseaseJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:35f14932-9d85-4a7e-8a5d-ddfa36ceea9eEnglishSymplectic ElementsElsevier2016Perniconi, BVauthier-Brouzes, DMorélot-Panzini, CDommergues, MNizard, JTaouagh, NHogrel, J-YCanal, AServais, LLaforêt, PPregnancy and delivery are challenging in women affected by Pompe disease with respiratory involvement. We describe a 28-year-old woman, who continued to receive enzyme replacement therapy during pregnancy and had an uneventful vaginal birth. Before pregnancy the patient's vital capacity was 52% in sitting position and 51% in supine position. At 32 weeks gestation her vital capacity in sitting position was 46% and 35% in supine position. Nocturnal non-invasive mechanical ventilation was introduced at this time. Labor was induced at 34 weeks following premature rupture of membranes, under epidural anesthesia. A 2590 g healthy baby was delivered by vacuum extraction. Assisted ventilation was continued throughout labor and post-partum. This observation suggests a successful pregnancy and a normal vaginal delivery can be achieved in patients with symptomatic Pompe Disease, provided multidisciplinary care is offered. |
| spellingShingle | Perniconi, B Vauthier-Brouzes, D Morélot-Panzini, C Dommergues, M Nizard, J Taouagh, N Hogrel, J-Y Canal, A Servais, L Laforêt, P Multidisciplinary care allowing uneventful vaginal delivery in a woman with Pompe disease |
| title | Multidisciplinary care allowing uneventful vaginal delivery in a woman with Pompe disease |
| title_full | Multidisciplinary care allowing uneventful vaginal delivery in a woman with Pompe disease |
| title_fullStr | Multidisciplinary care allowing uneventful vaginal delivery in a woman with Pompe disease |
| title_full_unstemmed | Multidisciplinary care allowing uneventful vaginal delivery in a woman with Pompe disease |
| title_short | Multidisciplinary care allowing uneventful vaginal delivery in a woman with Pompe disease |
| title_sort | multidisciplinary care allowing uneventful vaginal delivery in a woman with pompe disease |
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