Non-equivalent role of TM2 gating hinges in heteromeric Kir4.1/Kir5.1 potassium channels.
Comparison of the crystal structures of the KcsA and MthK potassium channels suggests that the process of opening a K(+) channel involves pivoted bending of the inner pore-lining helices at a highly conserved glycine residue. This bending motion is proposed to splay the transmembrane domains outward...
Main Authors: | Shang, L, Tucker, S |
---|---|
פורמט: | Journal article |
שפה: | English |
יצא לאור: |
2008
|
פריטים דומים
-
Identification of mutations in Kir5.1 which affect time-dependent activation of heteromeric Kir4.1/Kir5.1 potassium channels
מאת: Tucker, S, et al.
יצא לאור: (2002) -
Kir5.1 underlies long-lived subconductance levels in heteromeric Kir4.1/Kir5.1 channels from Xenopus tropicalis.
מאת: Shang, L, et al.
יצא לאור: (2009) -
Identification of a heteromeric interaction that influences the rectification, gating, and pH sensitivity of Kir4.1/Kir5.1 potassium channels.
מאת: Casamassima, M, et al.
יצא לאור: (2003) -
Identification of domains that control the heteromeric assembly of Kir5.1/Kir4.0 potassium channels.
מאת: Konstas, A, et al.
יצא לאור: (2003) -
Control of pH and PIP2 gating in heteromeric Kir4.1/Kir5.1 channels by H-Bonding at the helix-bundle crossing.
מאת: Rapedius, M, et al.
יצא לאור: (2007)