Combined HDAC and BET inhibition enhances melanoma vaccine immunogenicity and efficacy

The combined inhibition of histone deacetylases (HDAC) and the proteins of the bromodomain and extraterminal (BET) family have recently shown therapeutic efficacy against melanoma, pancreatic ductal adenocarcinoma, testicular, and lymphoma cancers in murine studies. However, in such studies, the rol...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: Badamchi-Zadeh, A, Moynihan, K, Larocca, R, Aid, M, Provine, N, Iampietro, M, Kinnear, E, Penaloza-Macmaster, P, Abbink, P, Blass, E, Tregoning, J, Irvine, D, Barouch, D
Format: Journal article
Język:English
Wydane: American Association of Immunologists 2018