Combined HDAC and BET inhibition enhances melanoma vaccine immunogenicity and efficacy
The combined inhibition of histone deacetylases (HDAC) and the proteins of the bromodomain and extraterminal (BET) family have recently shown therapeutic efficacy against melanoma, pancreatic ductal adenocarcinoma, testicular, and lymphoma cancers in murine studies. However, in such studies, the rol...
Main Authors: | Badamchi-Zadeh, A, Moynihan, K, Larocca, R, Aid, M, Provine, N, Iampietro, M, Kinnear, E, Penaloza-Macmaster, P, Abbink, P, Blass, E, Tregoning, J, Irvine, D, Barouch, D |
---|---|
פורמט: | Journal article |
שפה: | English |
יצא לאור: |
American Association of Immunologists
2018
|
פריטים דומים
-
Combined HDAC and BET Inhibition Enhances Melanoma Vaccine Immunogenicity and Efficacy
מאת: Badamchi-Zadeh, Alexander, et al.
יצא לאור: (2020) -
Adenovirus serotype 5 vaccine vectors trigger IL-27-dependent inhibitory CD4(+) T cell responses that impair CD8(+) T cell function
מאת: Larocca, R, et al.
יצא לאור: (2016) -
Immunogenicity and cross-reactivity of rhesus adenoviral vectors
מאת: Iampietro, M, et al.
יצא לאור: (2018) -
Immediate dysfunction of vaccine-elicited CD8+ T cells primed in the absence of CD4+ T cells
מאת: Provine, N, et al.
יצא לאור: (2016) -
Inhibitory receptor expression on memory CD8 T cells following Ad vector immunization
מאת: Penaloza-MacMaster, P, et al.
יצא לאור: (2016)