Combined HDAC and BET inhibition enhances melanoma vaccine immunogenicity and efficacy
The combined inhibition of histone deacetylases (HDAC) and the proteins of the bromodomain and extraterminal (BET) family have recently shown therapeutic efficacy against melanoma, pancreatic ductal adenocarcinoma, testicular, and lymphoma cancers in murine studies. However, in such studies, the rol...
主要な著者: | Badamchi-Zadeh, A, Moynihan, K, Larocca, R, Aid, M, Provine, N, Iampietro, M, Kinnear, E, Penaloza-Macmaster, P, Abbink, P, Blass, E, Tregoning, J, Irvine, D, Barouch, D |
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フォーマット: | Journal article |
言語: | English |
出版事項: |
American Association of Immunologists
2018
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