Combined HDAC and BET inhibition enhances melanoma vaccine immunogenicity and efficacy

The combined inhibition of histone deacetylases (HDAC) and the proteins of the bromodomain and extraterminal (BET) family have recently shown therapeutic efficacy against melanoma, pancreatic ductal adenocarcinoma, testicular, and lymphoma cancers in murine studies. However, in such studies, the rol...

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Detalhes bibliográficos
Principais autores: Badamchi-Zadeh, A, Moynihan, K, Larocca, R, Aid, M, Provine, N, Iampietro, M, Kinnear, E, Penaloza-Macmaster, P, Abbink, P, Blass, E, Tregoning, J, Irvine, D, Barouch, D
Formato: Journal article
Idioma:English
Publicado em: American Association of Immunologists 2018

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