Low penetrance breast cancer predisposition SNPs are site specific.

Low penetrance breast cancer predisposition SNPs are site specific.

Large scale association studies have identified low penetrance susceptibility alleles that predispose to breast cancer. A locus on chromosome 8q24.21 has been shown to harbour variants that predispose to breast, ovarian, colorectal and prostate cancer. The finding of risk variants clustering at 8q24...

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Dettagli Bibliografici
Autori principali:	Mcinerney, N, Colleran, G, Rowan, A, Walther, A, Barclay, E, Spain, S, Jones, A, Tuohy, S, Curran, C, Miller, N, Kerin, M, Tomlinson, I, Sawyer, E
Natura:	Journal article
Lingua:	English
Pubblicazione:	2009

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