An enzymatic approach to the desymmetrization of disubstituted pyrrolines.

An enzymatic approach to the desymmetrization of disubstituted pyrrolines.

The enzymatic desymmetrization of 2,2- and 2,5-disubstituted pyrroline compounds is reported in a procedure which gives access to both enantiomers in excellent enantiomeric excess and good yield. The enzyme reaction precursors are formed easily from two readily available substituted pyrroles using b...

Bibliografski detalji
Glavni autori:	Donohoe, T, Rigby, C, Thomas, R, Nieuwenhuys, W, Bhatti, F, Cowley, A, Bhalay, G, Linney, I
Format:	Journal article
Jezik:	English
Izdano:	2006

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