Nuclear factor I-C overexpression promotes monocytic development and cell survival in acute myeloid leukemia
Nuclear factor I-C (NFIC) belongs to a family of NFI transcription factors that binds to DNA through CAATT-boxes and are involved in cellular differentiation and stem cell maintenance. Here we show NFIC protein is significantly overexpressed in 69% of acute myeloid leukemia patients. Examination of...
Main Authors: | Rastogi, N, Gonzalez, JBM, Srivastava, VK, Alanazi, B, Alanazi, RN, Hughes, OM, O'Neill, NS, Gilkes, AF, Ashley, N, Deshpande, S, Andrews, R, Mead, A, Rodrigues, NP, Knapper, S, Darley, RL, Tonks, A |
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Format: | Journal article |
Language: | English |
Published: |
Springer Nature
2022
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