A randomized assessment of adding the kinase inhibitor lestaurtinib to first-line chemotherapy for FLT3-mutated AML

The clinical benefit of adding FMS-like tyrosine kinase-3 (FLT3)-directed small molecule therapy to standard first-line treatment of acute myeloid leukemia (AML) has not yet been established. As part of the UK AML15 and AML17 trials, patients with previously untreated AML and confirmed FLT3-activati...

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Detalhes bibliográficos
Main Authors: Knapper, S, Russell, N, Gilkes, A, Hills, RK, Gale, RE, Cavenagh, JD, Jones, G, Kjeldsen, L, Grunwald, MR, Thomas, I, Konig, H, Levis, MJ, Burnett, AK
Formato: Journal article
Idioma:English
Publicado em: American Society of Hematology 2017