Recent advances in dengue pathogenesis and clinical management.
This review describes and commentates on recent advances in the understanding of dengue pathogenesis and immunity, plus clinical research on vaccines and therapeutics. We expand specifically on the role of the dermis in dengue virus infection, the contribution of cellular and humoral immune response...
| প্রধান লেখক: | , , , , , , |
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| বিন্যাস: | Journal article |
| ভাষা: | English |
| প্রকাশিত: |
Elsevier
2015
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| _version_ | 1826267051526717440 |
|---|---|
| author | Simmons, C McPherson, K Van Vinh Chau, N Hoai Tam, D Young, P Mackenzie, J Wills, B |
| author_facet | Simmons, C McPherson, K Van Vinh Chau, N Hoai Tam, D Young, P Mackenzie, J Wills, B |
| author_sort | Simmons, C |
| collection | OXFORD |
| description | This review describes and commentates on recent advances in the understanding of dengue pathogenesis and immunity, plus clinical research on vaccines and therapeutics. We expand specifically on the role of the dermis in dengue virus infection, the contribution of cellular and humoral immune responses to pathogenesis and immunity, NS1 and mechanisms of virus immune evasion. Additionally we review a series of therapeutic intervention trials for dengue, as well as recent clinical research aimed at improving clinical diagnosis, risk prediction and disease classification. |
| first_indexed | 2024-03-06T20:48:17Z |
| format | Journal article |
| id | oxford-uuid:36afb3d4-01eb-4e3e-89bf-a3bb2b7fc76a |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T20:48:17Z |
| publishDate | 2015 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | oxford-uuid:36afb3d4-01eb-4e3e-89bf-a3bb2b7fc76a2022-03-26T13:39:27ZRecent advances in dengue pathogenesis and clinical management.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:36afb3d4-01eb-4e3e-89bf-a3bb2b7fc76aEnglishSymplectic Elements at OxfordElsevier2015Simmons, CMcPherson, KVan Vinh Chau, NHoai Tam, DYoung, PMackenzie, JWills, BThis review describes and commentates on recent advances in the understanding of dengue pathogenesis and immunity, plus clinical research on vaccines and therapeutics. We expand specifically on the role of the dermis in dengue virus infection, the contribution of cellular and humoral immune responses to pathogenesis and immunity, NS1 and mechanisms of virus immune evasion. Additionally we review a series of therapeutic intervention trials for dengue, as well as recent clinical research aimed at improving clinical diagnosis, risk prediction and disease classification. |
| spellingShingle | Simmons, C McPherson, K Van Vinh Chau, N Hoai Tam, D Young, P Mackenzie, J Wills, B Recent advances in dengue pathogenesis and clinical management. |
| title | Recent advances in dengue pathogenesis and clinical management. |
| title_full | Recent advances in dengue pathogenesis and clinical management. |
| title_fullStr | Recent advances in dengue pathogenesis and clinical management. |
| title_full_unstemmed | Recent advances in dengue pathogenesis and clinical management. |
| title_short | Recent advances in dengue pathogenesis and clinical management. |
| title_sort | recent advances in dengue pathogenesis and clinical management |
| work_keys_str_mv | AT simmonsc recentadvancesindenguepathogenesisandclinicalmanagement AT mcphersonk recentadvancesindenguepathogenesisandclinicalmanagement AT vanvinhchaun recentadvancesindenguepathogenesisandclinicalmanagement AT hoaitamd recentadvancesindenguepathogenesisandclinicalmanagement AT youngp recentadvancesindenguepathogenesisandclinicalmanagement AT mackenziej recentadvancesindenguepathogenesisandclinicalmanagement AT willsb recentadvancesindenguepathogenesisandclinicalmanagement |