E-cadherin marks a subset of inflammatory dendritic cells that promote T cell-mediated colitis.
Dendritic cells (DCs) play a pivotal role in controlling the balance between tolerance and immunity in the intestine. Gut conditioned CD103(+) DCs promote regulatory T (Treg) cell responses; however, little is known about DCs that drive inflammation in the intestine. Here, we show that monocyte-deri...
Hlavní autoři: | Siddiqui, K, Laffont, S, Powrie, F |
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Médium: | Journal article |
Jazyk: | English |
Vydáno: |
2010
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