E-cadherin marks a subset of inflammatory dendritic cells that promote T cell-mediated colitis.

Dendritic cells (DCs) play a pivotal role in controlling the balance between tolerance and immunity in the intestine. Gut conditioned CD103(+) DCs promote regulatory T (Treg) cell responses; however, little is known about DCs that drive inflammation in the intestine. Here, we show that monocyte-deri...

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Détails bibliographiques
Auteurs principaux: Siddiqui, K, Laffont, S, Powrie, F
Format: Journal article
Langue:English
Publié: 2010