Investigating break induced replication and template switching in fission yeast
<p>Single-stranded DNA breaks (SSBs) are the most common DNA lesion a cell can suffer with ~1 SSB formed every 5 seconds in a mammalian cell under normal conditions. Hence, a significant number of SSBs are encountered by replication forks in S-phase and these encounters can result in double-st...
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| Format: | Thesis |
| Language: | English |
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2022
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