Synthesis of (-)-xialenon A by enantioselective alpha-deprotonation-rearrangement of a meso-epoxide

Synthesis of (-)-xialenon A by enantioselective alpha-deprotonation-rearrangement of a meso-epoxide

The first total synthesis of (-)-xialenon A was achieved via enantioselective transannular desymmetrisation of a substituted cycloctene oxide using an organolithium/(-)-α-isosparteine combination. Oxidation of the resulting bicyclo[3.3.0]octanol gave an enone which underwent stereoselective conjugat...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों:	Hodgson, D, Galano, J, Christlieb, M
स्वरूप:	Journal article
भाषा:	English
प्रकाशित:	2003

समान संसाधन

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Enantioselective total synthesis of (-)-xialenon A.
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