Characterization of the molten globule state of retinol-binding protein using a molecular dynamics simulation approach.
Retinol-binding protein transports retinol, and circulates in the plasma as a macromolecular complex with the protein transthyretin. Under acidic conditions retinol-binding protein undergoes a transition to the molten globule state, and releases the bound retinol ligand. A biased molecular dynamics...
主要な著者: | , , , |
---|---|
フォーマット: | Journal article |
言語: | English |
出版事項: |
2005
|