Transcription-dependent gene looping of the HIV-1 provirus is dictated by recognition of pre-mRNA processing signals.

HIV-1 provirus, either as a chromosomal integrant or as an episomal plasmid in HeLa cells, forms a transcription-dependent gene loop structure between the 5'LTR promoter and 3'LTR poly(A) signal. Flavopiridol-mediated inhibition of RNA polymerase II elongation blocks 5' to 3'LTR...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Perkins, K, Lusic, M, Mitar, I, Giacca, M, Proudfoot, N
Fformat: Journal article
Iaith:English
Cyhoeddwyd: 2008