OXETANE NUCLEOSIDES WITH FLUORINE AND AZIDE SUBSTITUENTS - NUCLEOPHILIC DISPLACEMENTS ON AN OXETANE RING
Fluorine and azide substituents are introduced into an oxetane ring by nucleophilic displacement reactions; the syntheses and anti-viral activities of 9-(2′-azido-2′-deoxy-β-D-erythro-oxetanosyl)-adenine and of 9-(2′-deoxy-2′-fluoro-β-D-erythro-oxetanosyl)-adenine are reported. © 1991.
Bibliographic Details
Main Authors: |
Wang, Y,
Fleet, G,
Wilson, F,
Storer, R,
Myers, P,
Wallis, C,
Doherty, O,
Watkin, D,
Vogt, K,
Witty, D,
Peach, J |
Format: | Journal article
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Published: |
1991
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