OXETANE NUCLEOSIDES WITH FLUORINE AND AZIDE SUBSTITUENTS - NUCLEOPHILIC DISPLACEMENTS ON AN OXETANE RING
Fluorine and azide substituents are introduced into an oxetane ring by nucleophilic displacement reactions; the syntheses and anti-viral activities of 9-(2′-azido-2′-deoxy-β-D-erythro-oxetanosyl)-adenine and of 9-(2′-deoxy-2′-fluoro-β-D-erythro-oxetanosyl)-adenine are reported. © 1991.
Main Authors: | Wang, Y, Fleet, G, Wilson, F, Storer, R, Myers, P, Wallis, C, Doherty, O, Watkin, D, Vogt, K, Witty, D, Peach, J |
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Format: | Journal article |
Published: |
1991
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