Mathematical modelling of the ischaemic heart
Recent advances in high performance computing combined with increasing knowledge of the kinetics of biochemical reactions and transport processes have allowed us to develop mathematical models that describe various aspects of cardiac physiology. These models include both single cell and three-dimens...
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Format: | Conference item |
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2001
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author | Mulquiney, P Smith, N Clarke, K Hunter, P |
author_facet | Mulquiney, P Smith, N Clarke, K Hunter, P |
author_sort | Mulquiney, P |
collection | OXFORD |
description | Recent advances in high performance computing combined with increasing knowledge of the kinetics of biochemical reactions and transport processes have allowed us to develop mathematical models that describe various aspects of cardiac physiology. These models include both single cell and three-dimensional tissue models that simulate important features of cardiac electrophysiology, mechanics, and metabolism. We have begun to couple these models with the goal of creating a fully integrated cardiac model that can describe the pathophysiology of the ischaemic heart. Here we present an outline of this work. |
first_indexed | 2024-03-06T20:50:01Z |
format | Conference item |
id | oxford-uuid:373fc918-41e8-4687-af4a-04cdda24ef89 |
institution | University of Oxford |
last_indexed | 2024-03-06T20:50:01Z |
publishDate | 2001 |
record_format | dspace |
spelling | oxford-uuid:373fc918-41e8-4687-af4a-04cdda24ef892022-03-26T13:42:57ZMathematical modelling of the ischaemic heartConference itemhttp://purl.org/coar/resource_type/c_5794uuid:373fc918-41e8-4687-af4a-04cdda24ef89Symplectic Elements at Oxford2001Mulquiney, PSmith, NClarke, KHunter, PRecent advances in high performance computing combined with increasing knowledge of the kinetics of biochemical reactions and transport processes have allowed us to develop mathematical models that describe various aspects of cardiac physiology. These models include both single cell and three-dimensional tissue models that simulate important features of cardiac electrophysiology, mechanics, and metabolism. We have begun to couple these models with the goal of creating a fully integrated cardiac model that can describe the pathophysiology of the ischaemic heart. Here we present an outline of this work. |
spellingShingle | Mulquiney, P Smith, N Clarke, K Hunter, P Mathematical modelling of the ischaemic heart |
title | Mathematical modelling of the ischaemic heart |
title_full | Mathematical modelling of the ischaemic heart |
title_fullStr | Mathematical modelling of the ischaemic heart |
title_full_unstemmed | Mathematical modelling of the ischaemic heart |
title_short | Mathematical modelling of the ischaemic heart |
title_sort | mathematical modelling of the ischaemic heart |
work_keys_str_mv | AT mulquineyp mathematicalmodellingoftheischaemicheart AT smithn mathematicalmodellingoftheischaemicheart AT clarkek mathematicalmodellingoftheischaemicheart AT hunterp mathematicalmodellingoftheischaemicheart |