Interaction of anesthetics with open and closed conformations of a potassium channel studied via molecular dynamics and normal mode analysis.

Interaction of anesthetics with open and closed conformations of a potassium channel studied via molecular dynamics and normal mode analysis.

A variety of experiments suggest that membrane proteins are important targets of anesthetic molecules, and that ion channels interact differently with anesthetics in their open and closed conformations. The availability of an open and a closed structural model for the KirBac1.1 potassium channel has...

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Bibliografische gegevens
Hoofdauteurs:	Vemparala, S, Domene, C, Klein, M
Formaat:	Journal article
Taal:	English
Gepubliceerd in:	2008

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