Pharmacological and structural studies on the hedgehog pathway receptor smoothened
The Frizzled-class G protein-coupled receptor Smoothened (SMO) is an essential component of the Hedgehog (HH) signalling pathway, which is of paramount importance to developmental processes of bilaterians. Dysregulation of HH signalling has been implicated in multiple pathophysiological processes in...
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| Format: | Thesis |
| Language: | English |
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2023
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