Association of interleukin-1 gene polymorphisms with Alzheimer's disease.

Interleukin-1 (IL-1) is markedly overexpressed in Alzheimer's disease. We found the IL-1A 2,2 genotype in 12.9% of 232 neuropathologically confirmed Alzheimer's disease patients and 6.6% of 167 controls from four centers in the United Kingdom and United States (odds ratio, 3.0; controlled...

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Bibliographic Details
Main Authors: Nicoll, J, Mrak, R, Graham, D, Stewart, J, Wilcock, G, MacGowan, S, Esiri, M, Murray, L, Dewar, D, Love, S, Moss, T, Griffin, W
Format: Journal article
Language:English
Published: 2000