Asymmetric synthesis of cyclic beta-amino acids and cyclic amines via sequential diastereoselective conjugate addition and ring closing metathesis

Diastereoselective conjugate addition of lithium (S)-N-allyl-N-α-methylbenzylamide to a range of α,β-unsaturated esters followed by ring closing metathesis is used to afford efficiently a range of substituted cyclic β-amino esters in high d.e. Alternatively, conjugate addition to α,β-unsaturated Wei...

সম্পূর্ণ বিবরণ

গ্রন্থ-পঞ্জীর বিবরন
প্রধান লেখক: Chippindale, A, Davies, S, Iwamoto, K, Parkin, R, Smethurst, C, Smith, A, Rodriguez-Solla, H
বিন্যাস: Journal article
প্রকাশিত: 2003

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