Large-scale GWAS reveals genetic architecture of brain white matter microstructure and genetic overlap with cognitive and mental health traits (n = 17,706)

Large-scale GWAS reveals genetic architecture of brain white matter microstructure and genetic overlap with cognitive and mental health traits (n = 17,706)

Individual variations of white matter (WM) tracts are known to be associated with various cognitive and neuropsychiatric traits. Diffusion tensor imaging (DTI) and genome-wide single-nucleotide polymorphism (SNP) data from 17,706 UK Biobank participants offer the opportunity to identify novel geneti...

Deskribapen osoa

Xehetasun bibliografikoak
Egile Nagusiak:	Zhao, B, Zhang, J, Ibrahim, JG, Nichols, T, Et al.
Formatua:	Journal article
Hizkuntza:	English
Argitaratua:	Springer Nature 2019

Antzeko izenburuak

Analysis of protein-coding genetic variation in 60,706 humans.
nork: Lek, M, et al.
Argitaratua: (2016)

Genetic overlap between endometriosis and endometrial cancer: evidence from cross-disease genetic correlation and GWAS meta-analyses
nork: Painter, JN, et al.
Argitaratua: (2018)

The spatial correspondence and genetic influence of interhemispheric connectivity with white matter microstructure
nork: Mollink, J, et al.
Argitaratua: (2019)

Genetics of microstructure of cerebral white matter using diffusion tensor imaging.
nork: Kochunov, P, et al.
Argitaratua: (2010)

The spatial correspondence and genetic influence of interhemispheric connectivity with white matter microstructure
nork: Mollink, J, et al.
Argitaratua: (2019)

Within-sibship GWAS of 25 phenotypes improve estimates of direct genetic effects
nork: Howe, LJ, et al.
Argitaratua: (2022)

706 words of wisdom to be the happiest people
nork: Qurani, 'A'id ibn 'Abd Allah
Argitaratua: (2009)

Whole brain and regional hyperintense white matter volume and blood pressure: overlap of genetic loci produced by bivariate, whole-genome linkage analyses
nork: Kochunov, P, et al.
Argitaratua: (2010)

Colorectal cancer genetics: from candidate genes to GWAS and back again.
nork: Tomlinson, I
Argitaratua: (2012)

Behavioural relevance of variation in white matter microstructure.
nork: Johansen-Berg, H
Argitaratua: (2010)

Changes in white matter microstructure during adolescence.
nork: Giorgio, A, et al.
Argitaratua: (2008)

Developmental changes in white matter microstructure in adolescence
nork: Giorgio, A, et al.
Argitaratua: (2007)

Perhebat latih 209,706 veteran ATM
nork: Utusan, Malaysia
Argitaratua: (2016)

7.06 Cell Biology, Spring 2007
nork: Ploegh, Hidde, et al.
Argitaratua: (2023)

Polygenic prediction of occupational status GWAS elucidates genetic and environmental interplay in intergenerational transmission, careers and health in UK Biobank
nork: Akimova, ET, et al.
Argitaratua: (2024)

Genetic associations with white matter hyperintensities confer risk of lacunar stroke
nork: Traylor, M, et al.
Argitaratua: (2016)

Association genetics of wood physical traits in the conifer white spruce and relationships with gene expression.
nork: Beaulieu, J, et al.
Argitaratua: (2011)

Individual Differences in White Matter Microstructure in the Healthy Brain
nork: Scholz, J, et al.
Argitaratua: (2009)

Individual Differences in White Matter Microstructure in the Healthy Brain
nork: Scholz, J, et al.
Argitaratua: (2013)

Shared genetic aetiology between cognitive functions and physical and mental health in UK Biobank (N=112 151) and 24 GWAS consortia
nork: Hagenaars, SP, et al.
Argitaratua: (2016)

Reassessing associations between white matter and behaviour with multimodal microstructural imaging
nork: Lazari, A, et al.
Argitaratua: (2021)

GWAS.
nork: Flint, J
Argitaratua: (2013)

Investigating the genetic relationship between Alzheimer’s disease and cancer using GWAS summary statistics
nork: Feng, Y, et al.
Argitaratua: (2017)

GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19
nork: Pairo-Castineira, E, et al.
Argitaratua: (2023)

The rate of visuomotor adaptation correlates with cerebellar white-matter microstructure.
nork: Della-Maggiore, V, et al.
Argitaratua: (2009)

Genome-wide association study of intracranial aneurysms identifies 17 risk loci and genetic overlap with clinical risk factors
nork: Bakker, MK, et al.
Argitaratua: (2020)

The genetics of mental retardation.
nork: Flint, J, et al.
Argitaratua: (1996)

The effects of an aerobic training intervention on cognition, grey matter volumes and white matter microstructure
nork: Sexton, CE, et al.
Argitaratua: (2020)

Translating GWAS in rheumatic disease: approaches to establishing mechanism and function for genetic associations with ankylosing spondylitis
nork: Osgood, J, et al.
Argitaratua: (2018)

Common genetic variation indicates separate causes for periventricular and deep white matter hyperintensities
nork: Armstrong, NJ, et al.
Argitaratua: (2020)

Blood pressure and cerebral white matter share common genetic factors in Mexican Americans
nork: Kochunov, P, et al.
Argitaratua: (2011)

Genetic variation in PLEKHG1 is associated with white matter hyperintensities (n = 11,226)
nork: Traylor, M, et al.
Argitaratua: (2019)

Genetic analysis of variation in complex traits
nork: Groves-Kirkby, N
Argitaratua: (2016)

No genetic overlap between circulating iron levels and Alzheimer's disease
nork: Lupton, MK, et al.
Argitaratua: (2017)

Motor Skill Learning Induces Changes in White Matter Microstructure and Myelination
nork: Sampaio-Baptista, C, et al.
Argitaratua: (2013)

Detecting microstructural properties of white matter based on compartmentalization of magnetic susceptibility
nork: Chen, W, et al.
Argitaratua: (2012)

Motor skill learning induces changes in white matter microstructure and myelination.
nork: Sampaio-Baptista, S, et al.
Argitaratua: (2013)

[Genome sequencing and genetic mapping to dissect the genetic basis of complex traits].
nork: Baud, A, et al.
Argitaratua: (2013)

Affective traits of psychopathy are linked to white-matter tract abnormalities in impulsive offenders
nork: Vermeij, A, et al.
Argitaratua: (2018)

Evaluation of common genetic variants identified by GWAS for early onset and morbid obesity in population-based samples
nork: Den Hoed, M, et al.
Argitaratua: (2013)