Synthesis of taurospongin A and other biologically active natural products
<p>This thesis firstly describes a synthesis of the natural product taurospongin A, a potent DNA polymerase beta inhibitor. Sharpless asymmetric dihydroxylation on olefin <b><em>E</em>-1.60</b> followed by selective deoxygenation at C(2) via Barton‒McCombie reaction del...
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| Médium: | Diplomová práce |
| Jazyk: | English |
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2017
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