Synthesis of taurospongin A and other biologically active natural products
<p>This thesis firstly describes a synthesis of the natural product taurospongin A, a potent DNA polymerase beta inhibitor. Sharpless asymmetric dihydroxylation on olefin <b><em>E</em>-1.60</b> followed by selective deoxygenation at C(2) via Barton‒McCombie reaction del...
| Autore principale: | |
|---|---|
| Altri autori: | |
| Natura: | Tesi |
| Lingua: | English |
| Pubblicazione: |
2017
|
| Soggetti: |