Increased response to visual feedback of drug-induced dyskinetic movements in advanced Parkinson's disease.

To investigate the response to visual feedback of involuntary movements which have a frequency composition similar to cerebellar tremor but are not caused by cerebellar damage, we have tested six advanced Parkinson's disease (PD) patients with drug-induced dyskinetic movements using visually gu...

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Main Authors: Liu, X, Osterbauer, R, Aziz, T, Miall, R, Stein, J
Format: Journal article
Language:English
Published: 2001
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author Liu, X
Osterbauer, R
Aziz, T
Miall, R
Stein, J
author_facet Liu, X
Osterbauer, R
Aziz, T
Miall, R
Stein, J
author_sort Liu, X
collection OXFORD
description To investigate the response to visual feedback of involuntary movements which have a frequency composition similar to cerebellar tremor but are not caused by cerebellar damage, we have tested six advanced Parkinson's disease (PD) patients with drug-induced dyskinetic movements using visually guided wrist tracking tasks. Tracking performance was assessed under three visual conditions: (1) both guiding target and movement cursor were displayed continuously; (2) the target display was turned off for the second half of each trial; or (3) the cursor display, but not the target, was turned off for the second half of each trial. The response to visual feedback of drug-induced dyskinetic movements at 1-5 Hz in these advanced PD patients were significantly increased than in normal controls. This suggests that increased response to visual feedback might be a common feature of low frequency involuntary movements and not directly caused by cerebellar damages.
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spelling oxford-uuid:37aafe14-0c50-4f38-9d5e-8936360834892022-03-26T13:45:21ZIncreased response to visual feedback of drug-induced dyskinetic movements in advanced Parkinson's disease.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:37aafe14-0c50-4f38-9d5e-893636083489EnglishSymplectic Elements at Oxford2001Liu, XOsterbauer, RAziz, TMiall, RStein, JTo investigate the response to visual feedback of involuntary movements which have a frequency composition similar to cerebellar tremor but are not caused by cerebellar damage, we have tested six advanced Parkinson's disease (PD) patients with drug-induced dyskinetic movements using visually guided wrist tracking tasks. Tracking performance was assessed under three visual conditions: (1) both guiding target and movement cursor were displayed continuously; (2) the target display was turned off for the second half of each trial; or (3) the cursor display, but not the target, was turned off for the second half of each trial. The response to visual feedback of drug-induced dyskinetic movements at 1-5 Hz in these advanced PD patients were significantly increased than in normal controls. This suggests that increased response to visual feedback might be a common feature of low frequency involuntary movements and not directly caused by cerebellar damages.
spellingShingle Liu, X
Osterbauer, R
Aziz, T
Miall, R
Stein, J
Increased response to visual feedback of drug-induced dyskinetic movements in advanced Parkinson's disease.
title Increased response to visual feedback of drug-induced dyskinetic movements in advanced Parkinson's disease.
title_full Increased response to visual feedback of drug-induced dyskinetic movements in advanced Parkinson's disease.
title_fullStr Increased response to visual feedback of drug-induced dyskinetic movements in advanced Parkinson's disease.
title_full_unstemmed Increased response to visual feedback of drug-induced dyskinetic movements in advanced Parkinson's disease.
title_short Increased response to visual feedback of drug-induced dyskinetic movements in advanced Parkinson's disease.
title_sort increased response to visual feedback of drug induced dyskinetic movements in advanced parkinson s disease
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AT azizt increasedresponsetovisualfeedbackofdruginduceddyskineticmovementsinadvancedparkinsonsdisease
AT miallr increasedresponsetovisualfeedbackofdruginduceddyskineticmovementsinadvancedparkinsonsdisease
AT steinj increasedresponsetovisualfeedbackofdruginduceddyskineticmovementsinadvancedparkinsonsdisease