Structural and energetic aspects of multispecific immune recognition by NKG2D.

Structural and energetic aspects of multispecific immune recognition by NKG2D.

The multispecific immune receptor NKG2D binds different ligands using a different set of energetically dominant interface residues for each ligand.

Detalhes bibliográficos
Main Authors:	O'Callaghan, C, Jones, E
Formato:	Journal article
Idioma:	English
Publicado em:	2003

Registos relacionados

NKG2D
Por: O'Callaghan, C
Publicado em: (2009)

Regulation of ligands for the activating receptor NKG2D.
Por: Mistry, A, et al.
Publicado em: (2007)

Cellular metabolism controls NKG2D-dependent cellular immunogenicity
Por: McCarthy, M, et al.
Publicado em: (2013)

Molecular competition for NKG2D: H60 and RAE1 compete unequally for NKG2D with dominance of H60.
Por: O'Callaghan, C, et al.
Publicado em: (2001)

Natural killer cell surveillance of intracellular antigen processing pathways mediated by recognition of HLA-E and Qa-1b by CD94/NKG2 receptors.
Por: O'Callaghan, C
Publicado em: (2000)

Antibody multispecificity mediated by conformational diversity.
Por: James, L, et al.
Publicado em: (2003)

Inosine pranobex enhances human NK cell cytotoxicity by inducing metabolic activation and NKG2D ligand expression
Por: McCarthy, M, et al.
Publicado em: (2019)

Convergent evolution by cancer and viruses in evading the NKG2D immune response
Por: Baugh, R, et al.
Publicado em: (2020)

Multispecificity of a recombinant anti-ras monoclonal antibody
Por: Schrader, John W., et al.
Publicado em: (2017)

Cutting edge: the minor histocompatibility antigen H60 peptide interacts with both H-2Kb and NKG2D.
Por: Cerwenka, A, et al.
Publicado em: (2002)

Mechanisms of NKG2D ligand regulation
Por: McCarthy, M, et al.
Publicado em: (2013)

Single nucleotide polymorphism analysis of the NKG2D ligand cluster on the long arm of chromosome 6: Extensive polymorphisms and evidence of diversity between human populations.
Por: Antoun, A, et al.
Publicado em: (2010)

Expansion of circulating NKG2D+ effector memory T-cells and expression of NKG2D-ligand MIC in granulomaous lesions in Wegener's granulomatosis.
Por: Capraru, D, et al.
Publicado em: (2008)

Activation of innate and adaptive immunity by a recombinant human cytomegalovirus strain expressing an NKG2D ligand
Por: Tomić, A, et al.
Publicado em: (2016)

HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C.
Por: Braud, V, et al.
Publicado em: (1998)

NKG2D signaling is coupled to the interleukin 15 receptor signaling pathway
Por: Horng, T, et al.
Publicado em: (2007)

T Cells infiltrating diseased liver express ligands for the NKG2D stress surveillance system.
Por: Huang, W-C, et al.
Publicado em: (2017)

Experimental and computational analyses of the energetic basis for dual recognition of immunity proteins by colicin endonucleases.
Por: Keeble, A, et al.
Publicado em: (2008)

Inhibitory receptor signals suppress ligation-induced recruitment of NKG2D to GM1-rich membrane domains at the human NK cell immune synapse.
Por: Endt, J, et al.
Publicado em: (2007)

Intragenic transcriptional interference regulates the human immune ligand MICA
Por: Lin, D, et al.
Publicado em: (2018)

Molecular basis of human natural killer cell recognition of HLA-E (human leucocyte antigen-E) and its relevance to clearance of pathogen-infected and tumour cells.
Por: O'Callaghan, C
Publicado em: (2000)

Structure of the fungal beta-glucan-binding immune receptor dectin-1: implications for function.
Por: Brown, J, et al.
Publicado em: (2007)

Balance between activating NKG2D, DNAM-1, NKp44 and NKp46 and inhibitory CD94/NKG2A receptors determine natural killer degranulation towards rheumatoid arthritis synovial fibroblasts.
Por: Nielsen, N, et al.
Publicado em: (2014)

CD94/NKG2 is the predominant inhibitory receptor involved in recognition of HLA-G by decidual and peripheral blood NK cells.
Por: Söderström, K, et al.
Publicado em: (1997)

Recognition and blocking of innate immunity cells by Candida albicans chitin.
Por: Mora-Montes, H, et al.
Publicado em: (2011)

Thrombomodulation via CLEC-2 targeting.
Por: O'Callaghan, C
Publicado em: (2009)

A signal peptide derived from hsp60 binds HLA-E and interferes with CD94/NKG2A recognition.
Por: Michaëlsson, J, et al.
Publicado em: (2002)

Role of the crosstalk between CTLA-4 and NKG2D in the development of anti-CTLA-4 treatment strategies.
Por: Demaria, S, et al.
Publicado em: (2013)

A nanoscale reorganization of the IL-15 receptor is triggered by NKG2D in a ligand-dependent manner
Por: Bálint, Š, et al.
Publicado em: (2018)

STRUCTURE AND ENERGETICS OF THE ATMOSPHERE
Por: Taylor, F
Publicado em: (1982)

CLEC-2
Por: O'Callaghan, C, et al.
Publicado em: (2008)

The structure of the human allo-ligand HLA-B*3501 in complex with a cytochrome p450 peptide: steric hindrance influences TCR allo-recognition.
Por: Hourigan, C, et al.
Publicado em: (2006)

Crystal structure of rhodocytin, a ligand for the platelet-activating receptor CLEC-2.
Por: Watson, A, et al.
Publicado em: (2008)

Reduced glucose availability lowers MICA expression: a possible mechanism for tumour immune-evasion
Por: McCarthy, M, et al.
Publicado em: (2011)

Direct visualization of the immune response to cytomegalovirus (CMV) following renal transplantation.
Por: Jayawardene, SA, et al.
Publicado em: (2002)

Blockade of NKG2D ameliorates disease in mice with collagen-induced arthritis: a potential pathogenic role in chronic inflammatory arthritis.
Por: Andersson, A, et al.
Publicado em: (2011)

Cell surface organization of stress-inducible proteins ULBP and MICA that stimulate human NK cells and T cells via NKG2D.
Por: Eleme, K, et al.
Publicado em: (2004)

Structure and function of the CLEC-2 receptor and its ligands
Por: Watson, A, et al.
Publicado em: (2008)

BLOCKING THE INHIBITORY CD94/NKG2A NK CELL RECEPTOR WITH A NOVEL ANTI-NKG2A MAB ENHANCES THE SUSCEPTIBILITY OF RHEUMATOID ARTHRITIS FIBROBLAST-LIKE SYNOVIOCYTES (FLS) TO NK CELL-MEDIATED CYTOTOXICITY
Por: Nielsen, N, et al.
Publicado em: (2012)

Targeting NKG2D ligands in glioblastoma with a bispecific T-cell engager is augmented with conventional therapy and enhances oncolytic virotherapy of glioma stem-like cells
Por: Baugh, R, et al.
Publicado em: (2024)