Functional analysis of an oxygen-regulated transcriptional enhancer lying 3' to the mouse erythropoietin gene.
Erythropoietin, the major hormone controlling red-cell production, is regulated in part through oxygen-dependent changes in the rate of transcription of its gene. Using transient transfection in HepG2 cells, we have defined a DNA sequence, located 120 base pairs 3' to the poly(A)-addition site...
Main Authors: | Pugh, C, Tan, C, Jones, R, Ratcliffe, P |
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Format: | Journal article |
Language: | English |
Published: |
1991
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