[11C]-WAY100635 PET demonstrates marked 5-HT1A receptor changes in sporadic ALS.

[11C]-WAY100635 PET demonstrates marked 5-HT1A receptor changes in sporadic ALS.

The pathogenesis of amyotrophic lateral sclerosis (ALS) remains obscure, but it is now clear that neuronal loss is not confined to the motor cortex, even in cases without dementia. A reliable method of assessing cortical involvement in vivo remains elusive. WAY100635 binds selectively to the 5-hydro...

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Detalhes bibliográficos
Principais autores: Turner, M, Rabiner, E, Hammers, A, Al-Chalabi, A, Grasby, P, Shaw, C, Brooks, D, Leigh, P
Formato: Journal article
Idioma:English
Publicado em: 2005

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