Characterization of the CD4+ T cell response to Epstein-Barr virus during primary and persistent infection.
The CD8+ T cell response to Epstein-Barr virus (EBV) is well characterized. Much less is known about the evolution of the CD4+ T cell response. Here we show that EBV stimulates a primary burst of effector CD4+ T cells and this is followed by a period of down-regulation. A small population of EBV-spe...
Hauptverfasser: | Amyes, E, Hatton, C, Montamat-Sicotte, D, Gudgeon, N, Rickinson, AB, Mcmichael, A, Callan, M |
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Format: | Journal article |
Sprache: | English |
Veröffentlicht: |
2003
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