Design, recruitment, and microbiological considerations in human challenge studies.
Since the 18th century a wealth of knowledge regarding infectious disease pathogenesis, prevention, and treatment has been accumulated from findings of infection challenges in human beings. Partly because of improvements to ethical and regulatory guidance, human challenge studies-involving the delib...
Main Authors: | Darton, T, Blohmke, C, Moorthy, V, Altmann, D, Hayden, F, Clutterbuck, E, Levine, M, Hill, A, Pollard, A |
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Format: | Journal article |
Language: | English |
Published: |
Elsevier
2015
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