Ets-1 binds cooperatively to the palindromic Ets-binding sites in the p53 promoter.

Ets-1 binds cooperatively to the palindromic Ets-binding sites in the p53 promoter.

Due to its autoinhibition for DNA binding, the Ets-1 transcription factor must interact with partners to enhance its affinity for DNA. In a study on the stromelysin-1 promoter, we showed that Ets-1 binds cooperatively to two Ets-binding sites (EBS) organized in palindrome, thereby circumventing the...

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Bibliographic Details
Main Authors:	Baillat, D, Laitem, C, Leprivier, G, Margerin, C, Aumercier, M
Format:	Journal article
Language:	English
Published:	2009

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