Malignant melanoma and bone resorption.

Malignant melanoma and bone resorption.

The cellular and humoral mechanisms accounting for osteolysis in skeletal metastases of malignant melanoma are uncertain. Osteoclasts, the specialised multinucleated cells that carry out bone resorption, are derived from monocyte/macrophage precursors. We isolated tumour-associated macrophages (TAMs...

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Detalhes bibliográficos
Main Authors:	Lau, Y, Sabokbar, A, Giele, H, Cerundolo, V, Hofstetter, W, Athanasou, N
Formato:	Journal article
Idioma:	English
Publicado em:	2006

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