Structural basis for recognition of the pore-forming toxin intermedilysin by human complement receptor CD59.

Structural basis for recognition of the pore-forming toxin intermedilysin by human complement receptor CD59.

Pore-forming proteins containing the structurally conserved membrane attack complex/perforin fold play an important role in immunity and host-pathogen interactions. Intermedilysin (ILY) is an archetypal member of a cholesterol-dependent cytolysin subclass that hijacks the complement receptor CD59 to...

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Bibliographic Details
Main Authors:	Johnson, S, Brooks, N, Smith, R, Lea, S, Bubeck, D
Format:	Journal article
Language:	English
Published:	2013

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