Dual role of CO2/HCO3(-) buffer in the regulation of intracellular pH of three-dimensional tumor growths.

Dual role of CO2/HCO3(-) buffer in the regulation of intracellular pH of three-dimensional tumor growths.

Intracellular pH (pH(i)), a major modulator of cell function, is regulated by acid/base transport across membranes. Excess intracellular H(+) ions (e.g. produced by respiration) are extruded by transporters such as Na(+)/H(+) exchange, or neutralized by HCO(3)(-) taken up by carriers such as Na(+)-H...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Hulikova, A, Vaughan-Jones, R, Swietach, P
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	2011

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