Anaerobic crystallisation of an isopenicillin N synthase center dot Fe(II)center dot substrate complex demonstrated by X-ray studies

Anaerobic crystallisation of an isopenicillin N synthase center dot Fe(II)center dot substrate complex demonstrated by X-ray studies

Manylion Llyfryddiaeth
Prif Awduron:	Roach, P, Clifton, I, Hensgens, C, Shibata, N, Long, A, Strange, R, Hasnain, S, Schofield, C, Baldwin, J, Hajdu, J
Fformat:	Journal article
Cyhoeddwyd:	1996

Eitemau Tebyg

Anaerobic crystallisation of an isopenicillin N synthase.Fe(II).substrate complex demonstrated by X-ray studies.
gan: Roach, P, et al.
Cyhoeddwyd: (1996)

Structure of isopenicillin N synthase complexed with substrate and the mechanism of penicillin formation.
gan: Roach, P, et al.
Cyhoeddwyd: (1997)

Crystallization and preliminary X-ray diffraction studies on recombinant isopenicillin N synthase from Aspergillus nidulans.
gan: Roach, P, et al.
Cyhoeddwyd: (1995)

EXAFS STUDIES OF ISOPENICILLIN-N SYNTHASE
gan: Randall, C, et al.
Cyhoeddwyd: (1992)

Crystal structure of isopenicillin N synthase is the first from a new structural family of enzymes.
gan: Roach, P, et al.
Cyhoeddwyd: (1995)

Glutamine-330 is not essential for activity in isopenicillin N synthase from Aspergillus nidulans.
gan: Sami, M, et al.
Cyhoeddwyd: (1997)

ISOPENICILLIN-N SYNTHASE - A NEW MODE OF REACTIVITY
gan: Baldwin, J, et al.
Cyhoeddwyd: (1991)

ISOPENICILLIN-N SYNTHASE - A NEW MODE OF REACTIVITY
gan: Baldwin, J, et al.
Cyhoeddwyd: (1992)

Structural studies on the reaction of isopenicillin N synthase with the substrate analogue delta-(l-alpha-aminoadipoyl)-l-cysteinyl-d-alpha-aminobutyrate.
gan: Long, A, et al.
Cyhoeddwyd: (2003)

The crystal structure of isopenicillin N synthase with a dipeptide substrate analogue.
gan: Daruzzaman, A, et al.
Cyhoeddwyd: (2013)

FORMATION OF A NOVEL BICYCLIC GAMMA-LACTAM WITH ISOPENICILLIN-N SYNTHASE
gan: Baldwin, J, et al.
Cyhoeddwyd: (1989)

GAMMA-LACTAM FORMATION FROM TRIPEPTIDES WITH ISOPENICILLIN-N SYNTHASE
gan: Baldwin, J, et al.
Cyhoeddwyd: (1988)

Structural studies on the reaction of isopenicillin N synthase with the truncated substrate analogues delta-(L-alpha-aminoadipoyl)-L-cysteinyl-glycine and delta-(L-alpha-aminoadipoyl)-L-cysteinyl-D-alanine.
gan: Long, A, et al.
Cyhoeddwyd: (2005)

The crystal structure of an LLL-configured depsipeptide substrate analogue bound to isopenicillin N synthase.
gan: Ge, W, et al.
Cyhoeddwyd: (2010)

Molecular weight analysis of isopenicillin N synthase by electrospray mass spectrometry.
gan: Aplin, RT, et al.
Cyhoeddwyd: (1990)

Studies on side chain interactions during the isopenicillin N synthase catalysed biosynthesis of penicillins
gan: Cavelier, F, et al.
Cyhoeddwyd: (1997)

Crystallization and preliminary X-ray diffraction studies on a recombinant isopenicillin N synthase from Cephalosporium acremonium.
gan: Fujishima, Y, et al.
Cyhoeddwyd: (1994)

Crystallographic studies on the binding of selectively deuterated LLD- and LLL-substrate epimers by isopenicillin N synthase.
gan: Ge, W, et al.
Cyhoeddwyd: (2010)

Structural studies on the reaction of isopenicillin N synthase with a sterically demanding depsipeptide substrate analogue.
gan: Ge, W, et al.
Cyhoeddwyd: (2009)

Studies of isopenicillin N synthase enzymatic properties using a continuous spectrophotometric assay.
gan: Dubus, A, et al.
Cyhoeddwyd: (2000)

Mechanistic studies on isopenicillin n synthase
gan: Abbott, S
Cyhoeddwyd: (1991)

Roles of 2-oxoglutarate oxygenases and isopenicillin N synthase in ß-lactam biosynthesis
gan: Rabe, P, et al.
Cyhoeddwyd: (2018)

X-ray absorption studies of the ferrous active site of isopenicillin N synthase and related model complexes.
gan: Randall, C, et al.
Cyhoeddwyd: (1993)

Pb center dot center dot center dot pi aryl interactions as supramolecular synthons
gan: Tiekink, E.R.T., et al.
Cyhoeddwyd: (2010)

A theoretical treatment of the (A)over-tilde(2)Sigma(+) state of the Ar center dot center dot center dot HS/Ar center dot center dot center dot SH van der Waals complex
gan: Hirst, D, et al.
Cyhoeddwyd: (2004)

The interaction of isopenicillin N synthase with homologated substrate analogues δ-(L-α-aminoadipoyl)-L-homocysteinyl-D-Xaa characterised by protein crystallography.
gan: Daruzzaman, A, et al.
Cyhoeddwyd: (2013)

Spectroscopic studies reveal details of substrate-induced conformational changes distant from the active site in isopenicillin N synthase
gan: Rabe, P, et al.
Cyhoeddwyd: (2022)

Controlling the substrate selectivity of deacetoxycephalosporin/deacetylcephalosporin C synthase.
gan: Lloyd, MD, et al.
Cyhoeddwyd: (2004)

Isopenicillin N synthase mediates thiolate oxidation to sulfenate in a depsipeptide substrate analogue: implications for oxygen binding and a link to nitrile hydratase?
gan: Ge, W, et al.
Cyhoeddwyd: (2008)

Investigations into the post-translational modification and mechanism of isopenicillin N:acyl-CoA acyltransferase using electrospray mass spectrometry.
gan: Aplin, RT, et al.
Cyhoeddwyd: (1993)

Free and pulsed jet rotational spectra and van der Waals motions of ethanol center dot center dot center dot argon
gan: Maris, A, et al.
Cyhoeddwyd: (2004)

Modification of iron binding ligands in isopenicillin n synthase
gan: Sami, M, et al.
Cyhoeddwyd: (1998)

Contrasting nonclassical silicon-hydrogen interactions in niobium and tantalum half-sandwich complexes: Si-H center dot center dot center dot M agostic versus M-H center dot center dot center dot Si-Cl interligand hypervalent interactions
gan: Nikonov, G, et al.
Cyhoeddwyd: (2000)

The crystal structure of isopenicillin N synthase with δ-((L)-α-aminoadipoyl)-(L)-cysteinyl-(D)-methionine reveals thioether coordination to iron.
gan: Clifton, I, et al.
Cyhoeddwyd: (2011)

Isopenicillin N synthase binds δ-(L-α-aminoadipoyl)-L-cysteinyl-D-thia-allo-isoleucine through both sulfur atoms.
gan: Clifton, I, et al.
Cyhoeddwyd: (2011)

Surprising diversity of non-classical silicon-hydrogen interactions in half-sandivich complexes of Nb and Ta: M-H center dot center dot center dot Si-Cl interligand hypervalent interaction (IHI) versus stretched and unstretched beta-Si-H center dot center dot center dot M agostic bonding
gan: Nikonov, G, et al.
Cyhoeddwyd: (2001)

Proteins of the penicillin biosynthesis pathway.
gan: Schofield, C, et al.
Cyhoeddwyd: (1997)

Effects of nitrogen substitution in poly(pyrazolyl)borato ligands: From orbital energy levels to C-H center dot center dot center dot O hydrogen bonding
gan: Janiak, C, et al.
Cyhoeddwyd: (1996)

Photoaffinity labelling of isopenicillin N synthetase.
gan: Baldwin, J, et al.
Cyhoeddwyd: (1990)

Terminally truncated isopenicillin N synthase generates a dithioester product: evidence for a thioaldehyde intermediate during catalysis and a new mode of reaction for non-heme iron oxidases
gan: McNeill, LA, et al.
Cyhoeddwyd: (2017)