Germline epimutations of APC are not associated with inherited colorectal polyposis.

Germline epimutations of APC are not associated with inherited colorectal polyposis.

Bibliografiske detaljer
Main Authors:	Hitchins, M, Suter, C, Wong, J, Cheong, K, Hawkins, N, Leggett, B, Scott, R, Spigelman, A, Tomlinson, I, Martin, D, Ward, R
Format:	Journal article
Sprog:	English
Udgivet:	2006

Lignende værker

MLH1 germline epimutations as a factor in hereditary nonpolyposis colorectal cancer.
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Epigenetic inheritance, epimutation, and the response to selection.
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Epimutations, Inheritance and Causes of Aberrant DNA Methylation in Cancer
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Whole-gene APC deletions cause classical familial adenomatous polyposis, but not attenuated polyposis or "multiple" colorectal adenomas
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Whole-gene APC deletions cause classical familial adenomatous polyposis, but not attenuated polyposis or "multiple" colorectal adenomas.
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Germline Missense Changes in the APC Gene and Their Relationship to Disease
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EPHB2 germline variants in patients with colorectal cancer or hyperplastic polyposis
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Coinheritance of germline mutations in APC and MUTYH genes defines the clinical outcome of adenomatous polyposis syndromes
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<it>EPHB2 </it>germline variants in patients with colorectal cancer or hyperplastic polyposis
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Promoter hypermethylation leads to decreased APC mRNA expression in familial polyposis and sporadic colorectal tumours, but does not substitute for truncating mutations.
af: Segditsas, S, et al.
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The adenomatous polyposis coli (APC) tumour suppressor--genetics, function and disease.
af: Sieber, O, et al.
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Heterozygous APC germline mutations impart predisposition to colorectal cancer
af: Livia Preisler, et al.
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Identification of a novel germline APC N-terminal pathogenic variant associated with attenuated familial adenomatous polyposis
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Colorectal carcinomas arising in the hyperplastic polyposis syndrome progress through the chromosomal instability pathway.
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Germline APC mutations are not commonly seen in children with sporadic hepatoblastoma.
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Frequency of germline hereditary non-polyposis colorectal cancer gene mutations in patients with multiple or early onset colorectal adenomas.
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Investigation of pathogenic mechanisms in multiple colorectal adenoma patients without germline APC or MYH/MUTYH mutations.
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Tertiary Epimutations - A Novel Aspect of Epigenetic Transgenerational Inheritance Promoting Genome Instability.
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De novo familial adenomatous polyposis with germline double heterozygosity of APC/BRCA2: a case report and literature review
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A Novel Germline Mutation in Exon 15 of the APC Gene in Attenuated Familial Adenomatous Polyposis: A Report of Two Cases
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First Evidence of Familial Transmission of Hereditary Gastrointestinal Polyposis Associated with Germline <i>APC</i> Variant in Jack Russell Terriers
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Identification of 5 novel germline <it>APC </it>mutations and characterization of clinical phenotypes in Japanese patients with classical and attenuated familial adenomatous polyposis
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Familial adenomatous polyposis (FAP) and its gene, APC.
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Complete deletion of Apc results in severe polyposis in mice
af: Bronson, Roderick T., et al.
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The APC1310T/+ mouse: A novel murine model of intestinal tumorigenesis analogous to the APC-1309 mutation causing severe intestinal polyposis in humans
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Case Report: Coinheritance of Germline Mutations in APC and BRCA1 in Colorectal Cancer
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Germline APC variants in patients with multiple colorectal adenomas, with evidence for the particular importance of E1317Q.
af: Lamlum, H, et al.
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A neoepitope derived from a novel human germline APC gene mutation in familial adenomatous polyposis shows selective immunogenicity.
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Passing experiences on to future generations: endocrine disruptors and transgenerational inheritance of epimutations in brain and sperm
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Mercury-induced epigenetic transgenerational inheritance of abnormal neurobehavior is correlated with sperm epimutations in zebrafish.
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Author Correction: DNMT3L enables accumulation and inheritance of epimutations in transgenic Drosophila
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Vinclozolin induced epigenetic transgenerational inheritance of pathologies and sperm epimutation biomarkers for specific diseases.
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Dioxin (TCDD) induces epigenetic transgenerational inheritance of adult onset disease and sperm epimutations.
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The fluctuation of APC gene in WNT signaling with adenine deletion of adenomatous polyposis coli, is associated in colorectal cancer
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