Ca(2+) signaling occurs via second messenger release from intraorganelle synthesis sites.
Cyclic ADP-ribose is an important Ca(2+)-mobilizing cytosolic messenger synthesized from beta-NAD(+) by ADP-ribosyl cyclases (ARCs). However, the focus upon ectocellular mammalian ARCs (CD38 and CD157) has led to confusion as to how extracellular enzymes generate intracellular messengers in response...
Główni autorzy: | Davis, L, Morgan, A, Ruas, M, Wong, J, Graeff, R, Poustka, A, Lee, H, Wessel, G, Parrington, J, Galione, A |
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Format: | Journal article |
Język: | English |
Wydane: |
2008
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