In vivo effects of romidepsin on T-cell activation, apoptosis and function in the BCN02 HIV-1 kick&kill clinical trial

In vivo effects of romidepsin on T-cell activation, apoptosis and function in the BCN02 HIV-1 kick&kill clinical trial

Romidepsin (RMD) is a well-characterized histone deacetylase inhibitor approved for the treatment of cutaneous T-cell lymphoma. in vitro and in vivo studies have demonstrated that it is able to induce HIV-1 gene expression in latently infected CD4+ T cells from HIV-1+ individuals on suppressive anti...

Podrobná bibliografie
Hlavní autoři:	Rosás-Umbert, M, Ruiz-Riol, M, Fernández, MA, Marszalek, M, Coll, P, Manzardo, C, Cedeño, S, Miró, JM, Clotet, B, Hanke, T, Moltó, J, Mothe, B, Brander, C, BCN02 study group
Médium:	Journal article
Jazyk:	English
Vydáno:	Frontiers Media 2020

Podobné jednotky

In vivo Effects of Romidepsin on T-Cell Activation, Apoptosis and Function in the BCN02 HIV-1 Kick&Kill Clinical Trial
Autor: Miriam Rosás-Umbert, a další
Vydáno: (2020-03-01)

HIVconsv Vaccines and Romidepsin in Early-Treated HIV-1-Infected Individuals: Safety, Immunogenicity and Effect on the Viral Reservoir (Study BCN02)
Autor: Beatriz Mothe, a další
Vydáno: (2020-05-01)

HIVconsv vaccines and romidepsin in early-treated HIV-1-infected individuals: Safety, immunogenicity and effect on the viral reservoir (Study BCN02)
Autor: Mothe, B, a další
Vydáno: (2020)

Epigenetic landscape in the kick-and-kill therapeutic vaccine BCN02 clinical trial is associated with antiretroviral treatment interruption (ATI) outcome
Autor: Bruna Oriol-Tordera, a další
Vydáno: (2022-04-01)

Therapeutic vaccination refocuses t-cell responses towards conserved regions of HIV-1 in early treated individuals (BCN 01 study)
Autor: Mothe, B, a další
Vydáno: (2019)

Therapeutic Vaccination Refocuses T-cell Responses Towards Conserved Regions of HIV-1 in Early Treated Individuals (BCN 01 study)
Autor: Beatriz Mothe, a další
Vydáno: (2019-05-01)

Simvastatin-romidepsin combination kills bladder cancer cells synergistically
Autor: Kazuki Okubo, a další
Vydáno: (2021-09-01)

Landscape review of current HIV ‘kick and kill’ cure research - some kicking, not enough killing
Autor: Kristian Thorlund, a další
Vydáno: (2017-08-01)

Curing HIV by 'kick and kill': from theory to practice?
Autor: Pace, M, a další
Vydáno: (2019)

Gut microbiome signatures linked to HIV-1 reservoir size and viremia control
Autor: Alessandra Borgognone, a další
Vydáno: (2022-04-01)

Romidepsin in the treatment of cutaneous T-cell lymphoma
Autor: Jain S, a další
Vydáno: (2011-04-01)

Modeling Kick-Kill Strategies toward HIV Cure
Autor: Esteban A. Hernandez-Vargas
Vydáno: (2017-08-01)

Peripheral T cell lymphoma: clinical utility of romidepsin
Autor: Sawey K, a další
Vydáno: (2012-06-01)

Pharmacokinetics and Immunological Effects of Romidepsin in Rhesus Macaques
Autor: Adam J. Kleinman, a další
Vydáno: (2020-12-01)

Methodology for kick tolerance calculation and well killing in deepwater drilling
Autor: Yequan Jin, a další
Vydáno: (2016-11-01)

BCN20000: Dermoscopic Lesions in the Wild
Autor: Carlos Hernández-Pérez, a další
Vydáno: (2024-06-01)

Thermal Stability of SiBCN Films
Autor: Naohiro Hayashi, a další
Vydáno: (2008-10-01)

The Depsipeptide Romidepsin Reverses HIV-1 Latency In Vivo.
Autor: Ole S Søgaard, a další
Vydáno: (2015-09-01)

Romidepsin controls chronic lymphocytic leukemia in a patient with mycosis fungoides
Autor: David M. Lemchak, a další
Vydáno: (2016-11-01)

Disruption of the HLA-E/NKG2X axis is associated with uncontrolled HIV infections
Autor: Luis Romero-Martín, a další
Vydáno: (2022-11-01)

Projecto BCN: estratégias urbanas – geografias colectivas
Autor: Maria José Aurindo
Vydáno: (2010-08-01)

Long-Term Treatment with Romidepsin in Patients with Peripheral T-Cell Lymphoma
Autor: Claudius Irlé, a další
Vydáno: (2016-01-01)

Synergistic Effect Of Simvastatin And Romidepsin On Gamma-Globin Gene Induction
Autor: Hussain Habibi, a další
Vydáno: (2018-08-01)

25 Years of the International Bipolar Collaborative Network (BCN)
Autor: Robert M. Post, a další
Vydáno: (2021-04-01)

Romidepsin Enhances the Killing Ability of NKG2D-CAR-T Cells through Enhanced Expression of NKG2DL against Ovarian Cancer Cells
Autor: Liang Wang, a další
Vydáno: (2022-09-01)

Novel Csf/SiBCN composites prepared by densifying Csf/MA-SiBCN with the PIP process: Oxidation behavior and damage mechanism
Autor: Wenhao Dou, a další
Vydáno: (2024-05-01)

Treatment of Sezary syndrome with combination romidepsin and tofacitinib: A case report
Autor: Sara Suhl, BS, a další
Vydáno: (2025-01-01)

Llum BCN Festival d'Arts Lumíniques, 2020.
Autor: Teresa Pera Hospital
Vydáno: (2021-06-01)

On a Poisson–Lie deformation of the BCn Sutherland system
Autor: L. Fehér, a další
Vydáno: (2015-12-01)

Kicked drops
Autor: Chantelot, P, a další
Vydáno: (2018)

Super Rogers–Szegö polynomials associated with BCN type of Polychronakos spin chains
Autor: B. Basu-Mallick, a další
Vydáno: (2017-08-01)

28 Dendritic cells programmed by inflammatory mediators can effectively induce both the immunologic ‘kick’ and ‘kill’ of latent HIV-1
Autor: J. Kristoff, a další
Vydáno: (2016-07-01)

Mechanisms of abrupt loss of virus control in a cohort of previous HIV controllers
Autor: Rosás-Umbert, M, a další
Vydáno: (2018)

Multi-dose Romidepsin Reactivates Replication Competent SIV in Post-antiretroviral Rhesus Macaque Controllers.
Autor: Benjamin B Policicchio, a další
Vydáno: (2016-09-01)

MYCOSIS FUNGOIDES PROGRESSING TO PERIPHERAL T-CELL LYMPHOMA AND THE POTENTIAL ROLE OF ROMIDEPSIN THERAPY
Autor: Bengisu Ece Duman, a další
Vydáno: (2024-12-01)

Romidepsin Induces G2/M Phase Arrest and Apoptosis in Cholangiocarcinoma Cells
Autor: Pihong Li MD, a další
Vydáno: (2020-10-01)

BCN TAMPIL KEINDAHAN DAN KEUNIKAN TRADISI MASYARAKAT BORNEO
Autor: MPRC, Pusat Media & Perhubungan Awam
Vydáno: (2017)

Synthesis of three-dimensional BCN foam by template-assisted CVD
Autor: Fong, Gregory Xie Yi
Vydáno: (2018)

Strain dependent electronic and optical responses of penta-BCN monolayer
Autor: Shambhu Bhandari Sharma, a další
Vydáno: (2022-04-01)

On the classical r-matrix structure of the rational BCn Ruijsenaars–Schneider–van Diejen system
Autor: B.G. Pusztai
Vydáno: (2015-11-01)