Sympathetic-neuron-derived neuropeptide Y (NPY) regulates adipose tissue immunometabolic homeostasis

Sympathetic-neuron-derived neuropeptide Y (NPY) regulates adipose tissue immunometabolic homeostasis

<p>Neuropeptide Y (NPY) is secreted by sympathetic nerves (LUNDBERG et al.,1982; Lundberg, Franco-Cereceda, Hemsen, Lacroix, & Pernow, 1990), but its direct impact on thermogenic adipocytes is unknown. Here we uncover the mechanism by which peripheral NPY protects from obesity. Our ima...

Deskribapen osoa

Xehetasun bibliografikoak
Egile nagusia:	Zhu, Y
Beste egile batzuk:	Domingos, AI
Formatua:	Thesis
Hizkuntza:	English
Argitaratua:	2024
Gaiak:	Obesity Sympathetic nervous system

Antzeko izenburuak

Upregulation of neuropeptide Y in cardiac sympathetic nerves induces stress (Takotsubo) cardiomyopathy
nork: Takahide Arai, et al.
Argitaratua: (2022-11-01)

Carotid baroreceptor stimulation in obese rats affects white and brown adipose tissues differently in metabolic protection
nork: Quan Cao, et al.
Argitaratua: (2019-07-01)

Barosensory vessel mechanics and the vascular sympathetic baroreflex: Impact on blood pressure homeostasis
nork: Guto W. Hughes, et al.
Argitaratua: (2023-10-01)

Neuropeptide Y in the noradrenergic neurons induces the development of cardiometabolic diseases in a transgenic mouse model
nork: Suvi T Ruohonen, et al.
Argitaratua: (2012-01-01)

Getting Sympathetic About Air Pollution Exposure
nork: Robert D. Brook, et al.
Argitaratua: (2021-05-01)

Sympathetic innervation of interscapular brown adipose tissue is not a predominant mediator of Oxytocin (OT)-elicited reductions of body weight gain and adiposity in male diet-induced obese rats
nork: Melise M. Edwards, et al.
Argitaratua: (2024-12-01)

Developmental morphological characteristics of sympathetic ganglia in premature infants
nork: K. V. Dashichev, et al.
Argitaratua: (2024-06-01)

Sympathetic Pathways Target Cholinergic Neurons in the Human Colonic Myenteric Plexus
nork: Dominic R. Parker, et al.
Argitaratua: (2022-03-01)

Heart and neural crest derivative 2‐induced preservation of sympathetic neurons attenuates sarcopenia with aging
nork: Anna Carolina Zaia Rodrigues, et al.
Argitaratua: (2021-02-01)

Inclusion of Height and Limb Length when Interpreting Sympathetic Skin Response
nork: Mohamadreza Emad, et al.
Argitaratua: (2016-01-01)

Visualization of sympathetic neural innervation in human white adipose tissue
nork: Aliki Perdikari, et al.
Argitaratua: (2022-03-01)

Pathophysiological functions of semaphorins in the sympathetic nervous system
nork: Yumiko Mizuno, et al.
Argitaratua: (2023-06-01)

Visceral fat correlation with sympathetic neuronal activity in women
nork: Rama Kranthi, et al.
Argitaratua: (2014-06-01)

Clinical Relevance of the Sympathetic–Vascular Interactions in Health and Disease
nork: Fosca Quarti-Trevano, et al.
Argitaratua: (2021-08-01)

Role of α2-Adrenoceptors in Hypertension: Focus on Renal Sympathetic Neurotransmitter Release, Inflammation, and Sodium Homeostasis
nork: Lydia Hering, et al.
Argitaratua: (2020-11-01)

Peripheral sympathetic mechanisms in orofacial pain
nork: Fan W, et al.
Argitaratua: (2018-10-01)

Sympathetic Nervous System Mediates Cardiac Remodeling After Myocardial Infarction in a Circadian Disruption Model
nork: Yuhong Wang, et al.
Argitaratua: (2021-03-01)

Neuronal control of adaptive thermogenesis
nork: Xiaoyong eYang, et al.
Argitaratua: (2015-09-01)

The effect of bilateral cardiac sympathetic denervation for refractory ventricular tachycardia in ischemic cardiomyopathy
nork: Yuko Miki, et al.
Argitaratua: (2020-06-01)

Metaiodobenzylguanidine in the assessment of the ends of myocardial sympathetic fibers in patients with bronchial asthma
nork: S A Boitsov, et al.
Argitaratua: (2003-03-01)

The characteristics of autonomic nerve dysfunction and sympathetic skin response in patients with gout
nork: Li SONG, et al.
Argitaratua: (2019-07-01)

Consequences of spinal cord injury on the sympathetic nervous system
nork: Mariah J. Wulf, et al.
Argitaratua: (2023-02-01)

Adipose tissue macrophages: Regulators of adipose tissue immunometabolism during obesity
nork: Sierra A. Nance, et al.
Argitaratua: (2022-12-01)

Functional-Optical Coherence Tomography: A Non-invasive Approach to Assess the Sympathetic Nervous System and Intrinsic Vascular Regulation
nork: Nicholas G. Jendzjowsky, et al.
Argitaratua: (2019-09-01)

Sympathetic motor neuron dysfunction is a missing link in age-associated sympathetic overactivity
nork: Lizbeth de La Cruz, et al.
Argitaratua: (2024-12-01)

Sympathetic Nervous Influences Are Negative Prognostic Factors in Stomach Cancer
nork: Mihai Petrescu, et al.
Argitaratua: (2024-03-01)

On the number of preganglionic neurones driving human postganglionic sympathetic neurones: a comparison of modelling and empirical data
nork: Vaughan G Macefield
Argitaratua: (2011-12-01)

Peripheral blood flow regulation in response to sympathetic stimulation in individuals with down syndrome
nork: Thessa I.M. Hilgenkamp, et al.
Argitaratua: (2018-10-01)

Cardiac-sympathetic dysfunction in hypertension
nork: Bardsley, E
Argitaratua: (2018)

Effects of moxonidine on sympathetic nervous system activity: An update on metabolism, cardio, and other target-organ protection
nork: Eleni F Karlafti, et al.
Argitaratua: (2013-01-01)

Criteria for selecting patients with resistant hypertension for a renal sympathetic denervation
nork: T M Ripp, et al.
Argitaratua: (2016-08-01)

Impact of Obstructive Sleep Apnea and Sympathetic Nervous System on Cardiac Health: A Comprehensive Review
nork: Antonino Maniaci, et al.
Argitaratua: (2024-06-01)

Modulation of urethral alpha-sympathetic by parasympathetic before and following bethanechol chloride injection
nork: Haylton J. Suaid, et al.
Argitaratua: (2003-04-01)

Differential Sympathetic Activation of Adipose Tissues by Brain-Derived Neurotrophic Factor
nork: Qi Zhu, et al.
Argitaratua: (2019-09-01)

Sympathetic improvement of cancer vaccine efficacy
nork: Else Marit Inderberg, et al.
Argitaratua: (2020-08-01)

Centrally Projecting Edinger-Westphal Nucleus in the Control of Sympathetic Outflow and Energy Homeostasis
nork: Georgina Cano, et al.
Argitaratua: (2021-07-01)

O-GlcNAcylation is crucial for sympathetic neuron development, maintenance, functionality and contributes to peripheral neuropathy
nork: Hsueh-Fu Wu, et al.
Argitaratua: (2023-05-01)

SYMPATHETIC HYPERACTIVITY IN CHRONIC KIDNEY DISEASE PATIENTS: FROM PATHOGENESIS TO TREATMENT
nork: N. Stepanova
Argitaratua: (2017-12-01)

Delivery Mode Affects the Sympathetic Nervous System in Healthy Term Newborns
nork: Kozar Marek, et al.
Argitaratua: (2023-08-01)

Loss of chondroitin sulfate proteoglycan sulfation allows delayed sympathetic reinnervation after cardiac ischemia–reperfusion
nork: Matthew R. Blake, et al.
Argitaratua: (2023-05-01)