Investigating a role of HER3 in anti-HER2 target therapy in breast cancer

<p><em>Background</em></p> <p>HER2-positive breast cancer is a poor prognostic subgroup, even if treated with anti-HER2 directed therapy. Trastuzumab is an important HER2-targeting antibody but only limited patients respond to this drug, and acquired resistance is a com...

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Bibliographic Details
Main Author: Hashimoto, K
Other Authors: Kong, A
Format: Thesis
Language:English
Published: 2014
Subjects: