A single dose of ChAdOx1 Chik vaccine induces neutralising antibodies against four chikungunya virus lineages in a phase 1 clinical trial
Chikungunya virus (CHIKV) is a reemerging mosquito-borne virus that causes swift outbreaks. Major concerns are the persistent and disabling polyarthralgia in infected individuals. Here we present the results from a first-in-human trial of the candidate simian adenovirus vectored vaccine ChAdOx1 Chik...
Main Authors: | Folegatti, P, Harrison, K, Preciado-Llanes, L, Ramos Lopez, F, Bittaye, M, Kim, Y, Flaxman, A, Bellamy, D, Makinson, R, Sheridan, J, Tilley, M, Tran, N, Jenkin, D, Poulton, I, Lawrie, A, Roberts, R, Berrie, E, Hill, A, Ewer, K, Reyes-Sandoval, A |
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Format: | Journal article |
Language: | English |
Published: |
Springer Nature
2021
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