XRCC1-DNA polymerase beta interaction is required for efficient base excision repair.
X-ray repair cross-complementing protein-1 (XRCC1)-deficient cells are sensitive to DNA damaging agents and have delayed processing of DNA base lesions. In support of its role in base excision repair, it was found that XRCC1 forms a tight complex with DNA ligase IIIalpha and also interacts with DNA...
Հիմնական հեղինակներ: | Dianova, I, Sleeth, K, Allinson, S, Parsons, J, Breslin, C, Caldecott, K, Dianov, G |
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Ձևաչափ: | Journal article |
Լեզու: | English |
Հրապարակվել է: |
2004
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Նմանատիպ նյութեր
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DNA polymerase beta promotes recruitment of DNA ligase III alpha-XRCC1 to sites of base excision repair.
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Հրապարակվել է: (2005) -
Repair of abasic sites in DNA.
: Dianov, G, և այլն
Հրապարակվել է: (2003) -
XRCC1 phosphorylation by CK2 is required for its stability and efficient DNA repair.
: Parsons, J, և այլն
Հրապարակվել է: (2010) -
Orchestration of base excision repair by controlling the rates of enzymatic activities.
: Allinson, S, և այլն
Հրապարակվել է: (2004) -
Poly(ADP-ribose) polymerase-1 protects excessive DNA strand breaks from deterioration during repair in human cell extracts.
: Parsons, J, և այլն
Հրապարակվել է: (2005)