Hepatitis C virus envelope glycoprotein fitness defines virus population composition following transmission to a new host.

Hepatitis C virus envelope glycoprotein fitness defines virus population composition following transmission to a new host.

Genetic variability is a hallmark of RNA virus populations. However, transmission to a new host often results in a marked decrease in population diversity. This genetic bottlenecking is observed during hepatitis C virus (HCV) transmission and can arise via a selective sweep or through the founder ef...

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Bibliographic Details
Main Authors:	Brown, R, Hudson, N, Wilson, G, Rehman, S, Jabbari, S, Hu, K, Tarr, A, Borrow, P, Joyce, M, Lewis, J, Zhu, L, Law, M, Kneteman, N, Tyrrell, D, McKeating, J, Ball, J
Format:	Journal article
Language:	English
Published:	2012

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