Fibroblast-like synoviocytes orchestrate daily rhythmic inflammation in arthritis
Rheumatoid arthritis is a chronic inflammatory disease that shows characteristic diurnal variation in symptom severity, where joint resident fibroblast-like synoviocytes (FLS) act as important mediators of arthritis pathology. We investigate the role of FLS circadian clock function in directing rhyt...
Main Authors: | Downton, P, Dickson, SH, Ray, DW, Bechtold, DA, Gibbs, JE |
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格式: | Journal article |
语言: | English |
出版: |
The Royal Society
2024
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