T cell receptors are structures capable of initiating signaling in the absence of large conformational rearrangements.

Native and non-native ligands of the T cell receptor (TCR), including antibodies, have been proposed to induce signaling in T cells via intra- or intersubunit conformational rearrangements within the extracellular regions of TCR complexes. We have investigated whether any signatures can be found for...

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Bibliographic Details
Main Authors: Fernandes, R, Shore, D, Vuong, M, Yu, C, Zhu, X, Pereira-Lopes, S, Brouwer, H, Fennelly, J, Jessup, C, Evans, E, Wilson, I, Davis, S
Format: Journal article
Language:English
Published: 2012