An asymmetric Suzuki-Miyaura approach to prostaglandins: Synthesis of Tafluprost
We report the catalytic asymmetric synthesis of Tafluprost (1), a prostaglandin analogue. This synthesis demonstrates a new approach to prostaglandins involving symmetrization and desymmetrization of a racemic precursor to control the absolute and relative stereochemistry of the cyclopentyl core. Ke...
| Prif Awduron: | , , |
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| Fformat: | Journal article |
| Iaith: | English |
| Cyhoeddwyd: |
American Chemical Society
2020
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